Pardo, José V., M.D., Ph.D.

QUANTITATIVE NEUROIMAGING/PSYCHIATRY

Brain Imaging and Cognitive Neuroscience. We seek to elucidate the functional architecture of the human brain at the level of brain maps through application of imaging modalites (PET, fMRI, MEG, ERP), chronometry, and psychophysiology. Both control subjects and patients with various neuropsychiatric disorders participate in the research. An understanding of normal cognition will provide the infrastructure to study the pathophysiology of psychiatric brain disorders. Specific projects currently active and led by various members of the Cognitive Neuroimaging Unit and collaborators include the following: • language processing in schizophrenia • fear processing in PTSD • brain metabolism in treatment-refractory unipolar depression • cognitive architecture of the medial temporal lobe in the young and aging • spatial and motion processing in the somatosensory system • affect processing in sensory systems and the modulation of drive states through drugs • imaging appetitive behaviors • neuronal basis of choice